Everything To Guppy

A near-daily podcast about the items and lore in the Binding Of Isaac.

About the show

William Hughes (The A.V. Club) and Gary Butterfield (Watch Out for Fireballs!) get together four times a week to talk through every single item, trinket, boss, monster, and, really, everything in Edmund McMillen's "The Binding Of Isaac". New, bite-sized episodes come out every Tuesday, Thursday, Saturday, and Sunday.


  • Episode 413: Strange Attractor

    February 4th, 2020  |  16 mins 47 secs

    Everywhere in the village, entropy began to slurp the margins of reality into its unrelenting and toddler-like grip.

  • Episode 412: Chapter 1

    February 3rd, 2020  |  18 mins 10 secs

    The bird struggled, briefly, before a careless movement snapped its fragile neck, and with slow deliberation, the "child" began pulling its parent into the shadowed recesses of its red-tinged and hungry shell.

  • Episode 411: Thunder Thighs

    February 1st, 2020  |  18 mins 15 secs

    One unlucky fowl moved too slowly; the tentacle that oozed from the cracks in its own fresh-laid egg was around its throat as quick as its lidless eye could blink.

  • Episode 410: Holy Mantle

    January 30th, 2020  |  16 mins 1 sec

    In henhouses throughout the valley, chickens began pecking dementedly at their own eggs, blood gushing from the crushed shells.

  • Episode 409: Maggy's Bow

    January 28th, 2020  |  18 mins 46 secs

    Throughout the village, clocks began to chime hexteen, announcing that the Bewatching Hour had arrived at longest last

  • Episode 408: Mama Gurdy

    January 26th, 2020  |  15 mins 52 secs

    Evil might be afoot in Harkneass Manor, but that only meant that it was time for Harvey Mouse, Daredevil—The Bravest Little Mouse In The Whole Wide World—to do what he did best.

  • Episode 407: Judas' Shadow

    January 25th, 2020  |  12 mins 43 secs

    His paws moved, slightly nervous, over the cool plastic handlebars of his cherry-red motorcycle; then dashed into action as its tiny motor roared into adorable life.

  • Episode 406: Eve's Mascara

    January 23rd, 2020  |  14 mins 58 secs

    He had seen the signs before, of course; his whiskers twitched, in pain and memory, at the thought of the madness that had gone down in Heriksberg 14 years previous.

  • Episode 405: Pisces

    January 21st, 2020  |  17 mins 2 secs

    And yet even as this host of damned souls found themselves spiraling, inexorably, toward the doom in the castle, another figure watched these developments with a sense of concern and unease.

  • Episode 404: Cursed Skull

    January 19th, 2020  |  17 mins 32 secs

    "The trouble with being a Haunted Midwife," she thought, grabbing the bag from near her door, "Is that the Devil makes sure you always deliver."

  • Episode 403: Aquarius

    January 18th, 2020  |  9 mins 12 secs

    Sympathy scraping at her toenails, she keened helplessly alongside that orphaned wail.

  • Episode 402: Capricorn

    January 16th, 2020  |  12 mins 27 secs

    Obscured by a web of eldritch secrecy that obfuscated her identity—even from herself—she immediately felt the keening of a secret-sister-spirit calling to her from across the hangry ether.

  • Episode 401: Sagittarius

    January 14th, 2020  |  15 mins 49 secs

    Across the village, in a hovel that was distinctly hovel-shaped, a Secret Witch awoke.

  • Episode 400: Curses

    January 12th, 2020  |  23 mins 48 secs

    Tearing the bauble from his neck with a hornedy grunt, the hunter put his head down and began trudging once again into the sickly sweet claws of the inky, tenebrous night.

  • Episode 399: Scorpio

    January 11th, 2020  |  9 mins 54 secs

    As though summoned by the very thought, it began to suddenly twist its way around his throat, the silver chain digging into the folds of fat that hung like ulcerous fruits from his chin's mottled skin.

  • Episode 398: Libra

    January 9th, 2020  |  13 mins 34 secs

    As he solemnly watched, the chunk of vulpine cranium hanging from his neck began to kick and twist like a hanged man's final, mirthless jig.