Everything To Guppy

A near-daily podcast about the items and lore in the Binding Of Isaac.

About the show

William Hughes (The A.V. Club) and Gary Butterfield (Watch Out for Fireballs!) get together four times a week to talk through every single item, trinket, boss, monster, and, really, everything in Edmund McMillen's "The Binding Of Isaac". New, bite-sized episodes come out every Tuesday, Thursday, Saturday, and Sunday.


  • Episode 244: Pinky Eye

    April 14th, 2019  |  13 mins 44 secs

    This eye is pinky, and are you pondering What I'm pondering?

  • Episode 243: Blood Rights

    April 13th, 2019  |  12 mins 27 secs

    These rights are for blood, and these cannibalisTic humanoid underground dwellers are C.H.U.D.s!

  • Episode 242: Dead Dove

    April 11th, 2019  |  11 mins 39 secs

    This dove is dead, and MAtt Hazard eats lead!

  • Episode 241: Holy Grail

    April 9th, 2019  |  13 mins 27 secs

    This grail is holy, and my favorite kind of garlic-y mayonnaisE is aioli!

  • Episode 240: The Wretched

    April 7th, 2019  |  13 mins 18 secs

    This dead spider is wretched, and My favorite kind of glass is etched!

  • Episode 239: Toothpicks

    April 6th, 2019  |  10 mins 38 secs

    Normally I Do a cute little rhyme here, but I'll lay it out on the line for you, folks: This is challenging episode.

  • Episode 238: Sacred Heart

    April 4th, 2019  |  10 mins 1 sec

    This heart is sacred, aNd my favorite verb-color combination is bake-red!

  • Episode 237: White Pony

    April 2nd, 2019  |  11 mins 10 secs

    This pony is whitE, and it grants you flight!

  • Episode 236: Cain

    March 31st, 2019  |  13 mins 38 secs

    This fun fellow is Cain, and he's inSane, in the mem-brain!

  • Episode 235: The Black Bean

    March 30th, 2019  |  16 mins 24 secs

    This bean is black, and "Lola" is a sOng by The Knack!

  • Episode 234: Fate

    March 28th, 2019  |  12 mins 43 secs

    There's no fate but what we make, and no cake but wHat we bake!

  • Episode 233: Holy Water

    March 26th, 2019  |  12 mins 21 secs

    This water is holy, and Why is this item in the game?

  • Episode 232: Fish Head

    March 24th, 2019  |  15 mins 29 secs

    This head camE from a fish, and if you're in heaven, you get a wish!

  • Episode 231: Portable Slot

    March 23rd, 2019  |  15 mins 58 secs

    This slot is portabLe, and the average pair of blue jeans is secretly jortable!

  • Episode 230: Stem Cells

    March 21st, 2019  |  11 mins 18 secs

    These cells come from stems, and my favorite Part of dresses are the hems!

  • Episode 229: Dad's Key

    March 19th, 2019  |  9 mins

    This key is Dad's, and an infOrmal name for radiation is rads!