Everything To Guppy

A near-daily podcast about the items and lore in the Binding Of Isaac.

About the show

William Hughes (The A.V. Club) and Gary Butterfield (Watch Out for Fireballs!) get together four times a week to talk through every single item, trinket, boss, monster, and, really, everything in Edmund McMillen's "The Binding Of Isaac". New, bite-sized episodes come out every Tuesday, Thursday, Saturday, and Sunday.


  • Episode 631: Mom

    February 28th, 2021  |  17 mins 16 secs

    Friendship Ranger 3 only wished (in an absent and paternal sort of way) that their screams of gratitude weren't quite so loud, or so tinged with the higher octaves of a vocal cord gleefully shredding itself in happiness.

  • Episode 630: Glyph Of Balance

    February 27th, 2021  |  15 mins 19 secs

    Why else would the Feelings Felons be so effusively, weepingly thankful after having their rogue brainwaves forcibly corrected?

  • Episode 629: Sulfuric Acid

    February 25th, 2021  |  11 mins 43 secs

    But closer analysis of these aberrant emoto-clusters—performed after scooping the related neurons out of the offending minds with the help of the Cuddle Police's smiling Adjustment Technicians—showed them to be in error.

  • Episode 628: Eye Of Belial

    February 23rd, 2021  |  15 mins 46 secs

    People sometimes argued—in what they thought were their secure Secret Sometimes Feeling Vaults—that Mutually Enforced Happiness had its downsides.

  • Episode 627: Rainbow Worm

    February 21st, 2021  |  9 mins 19 secs

    Friendship Ranger 3 tried not to indulge in pride (a sin), but he had to admit that it felt good to have saved the world, forever, from itself.

  • Episode 626: Parasitoid

    February 20th, 2021  |  12 mins 7 secs

    He waved cheerfully at a woman walking her handsome and highly toothed baby, and screamed back at him with the happy shrieks of the terminally fulfilled.

  • Episode 625: Glaucoma

    February 18th, 2021  |  11 mins 7 secs

    Everywhere Friendship Ranger 3 walked, he saw smiling, happy people, barely even writhing in their Mandatory Joy Harnesses.

  • Episode 624: Sinus Infection

    February 16th, 2021  |  11 mins 27 secs

    And so he bolted his High Performance Amblin' Boots to his Bottom-Hands and made his way out into the world.

  • Episode 623: The Seven Deadly Sins Pt. 4

    February 14th, 2021  |  15 mins 3 secs

    Then he remembered that all his vehicles had been sold to charity when he converted his garage, so instead he would have to walk.

  • Episode 622: The Seven Deadly Sins Pt. 3

    February 13th, 2021  |  18 mins 39 secs

    Or should he hop into the sidecar of the Getting Tickled Motorcycle?

  • Episode 621: The Seven Deadly Sins Pt. 2

    February 11th, 2021  |  13 mins 49 secs

    Would this be a proper day to take a trip in the Huggles Bus?

  • Episode 620: The Seven Deadly Sins Pt. 1

    February 9th, 2021  |  14 mins 11 secs

    Walking into his super-cool converted garage, he wondered which of his Friendship vehicles he should take to the Friendship Office today.

  • Episode 619: Safety Scissors

    February 7th, 2021  |  11 mins 31 secs

    Either way, with the support of the other members of the Friendship Force 5, Friendship Ranger 3 knew that those frowns could be forcibly turned upside down.

  • Episode 618: Belly Button

    February 6th, 2021  |  10 mins

    Who could it be—The Slumpos? King Crybaby? Seasonal Affective Disco Stu?

  • Episode 617: Cone Head

    February 4th, 2021  |  12 mins 33 secs

    Today's sensors were pointing due despairgasm.

  • Episode 616: Moldy Bread

    February 2nd, 2021  |  13 mins 30 secs

    The Friendship Organs were calibrated to respond to many orgone flavors, from smiles to murderfrown.