Everything To Guppy

A near-daily podcast about the items and lore in the Binding Of Isaac.

About the show

William Hughes (The A.V. Club) and Gary Butterfield (Watch Out for Fireballs!) get together four times a week to talk through every single item, trinket, boss, monster, and, really, everything in Edmund McMillen's "The Binding Of Isaac". New, bite-sized episodes come out every Tuesday, Thursday, Saturday, and Sunday.


  • Episode 779: Dim Bulb

    November 30th, 2021  |  14 mins

    Acoustic guitar suddenly came blaring into the car's stereo, threatening to send everyone inside into a fatal groove.

  • Episode 778: Sulfur

    November 27th, 2021  |  10 mins 15 secs

    "Buckle in, folks," he said, buckling in, "I think we're facing a Norm Corps attack."

  • Episode 777: Vibrant Bulb

    November 26th, 2021  |  9 mins 4 secs

    His eyes quickly scanned for the telltale signs on the ordnance, of a long-sleeved camo pattern with a T-shirt underneath.

  • Episode 776: Super Ball

    November 24th, 2021  |  13 mins 32 secs

    Glancing out the car window, he saw a plaid missile attached to the passenger side door.

  • Episode 775: Nose Goblin

    November 22nd, 2021  |  10 mins 41 secs

    Friendship Ranger 3 was suddenly shaken out of his reverie by a sudden shaking.

  • Episode 774: Rainmaker

    November 21st, 2021  |  17 mins 8 secs

    Either way, he'd probably get a cool new superhero outfit out of it.

  • Episode 773: Tonsil (Trinket)

    November 20th, 2021  |  14 mins 7 secs

    Or they'd all be dead, which seemed reasonably likely, too.

  • Episode 772: Ouroboros Worm

    November 18th, 2021  |  13 mins 50 secs

    He thrilled at the thought that some day everyone would feel this same sense of one-ness.

  • Episode 771: Black Tooth

    November 16th, 2021  |  13 mins 38 secs

    Friendship Ranger 3 still remembered the thrilling feeling of being connected to others, a beautiful Tumblring of the spirit.

  • Episode 770: The Everything To Guppy Halloween Spooktacular 2021: Wingin' It and Wingsin' It With Will Edition

    November 9th, 2021  |  1 hr 48 mins

    Everything To Guppy is normally an improvised comedy show about the Binding Of Isaac. This week, it's a commentary track for Episodes 4.15 and 4.16 (The Gift Pt. 1 and The Gift Pt. 2) of the NBC sitcom Wings. No, they're not on Hulu.

    This might be the dumbest one we've done.

  • Episode 769: Golden Razor

    November 7th, 2021  |  17 mins 2 secs

    But once the WiFi antennas finished growing up through their spines, connection became much quicker.

  • Episode 768: Fish Tail

    November 6th, 2021  |  10 mins 30 secs

    The debilitating pain and negative effect on buses made the going slow at first.

  • Episode 767: Used Diaper

    November 4th, 2021  |  12 mins 39 secs

    They were spread across a globe unaware of the emotional bear hug it was now being prepped for.

  • Episode 766: Cracked Crown

    November 2nd, 2021  |  15 mins 23 secs

    It took a few days to find the others who had been, for lack of a better word, chosen.

  • Episode 765: Clog

    October 31st, 2021  |  15 mins 9 secs

    It also meant freedom from taxes, because of the whole "being dead" thing.

  • Episode 764: Meconium

    October 30th, 2021  |  18 mins 27 secs

    But free to know that anything he now found himself compelled to do was right.