Everything To Guppy

A near-daily podcast about the items and lore in the Binding Of Isaac.

About the show

William Hughes (The A.V. Club) and Gary Butterfield (Watch Out for Fireballs!) get together four times a week to talk through every single item, trinket, boss, monster, and, really, everything in Edmund McMillen's "The Binding Of Isaac". New, bite-sized episodes come out every Tuesday, Thursday, Saturday, and Sunday.


  • Episode 855: The KR-ZONE: Free Lemonade - Spirit Sword - Red Key - Torn Card

    May 17th, 2022  |  1 hr 17 mins

    This week's episodes: Free Lemonade, Spirit Sword, Red Key, and Torn Card.

  • Episode 854: Intruder - Dirty Mind - Damocles - The Siren

    May 10th, 2022  |  1 hr 5 mins

    Apologies for the late upload this week!

    Today's episodes: Intruder, Dirty Mind, Damocles, and The Siren.

  • Episode 853: Eye Of The Occult - Immaculate Heart - Monstrance - Mom's Kiss

    May 3rd, 2022  |  1 hr 3 mins

    This week's episodes: Eye Of The Occult, Immaculate Heart, Monstrace, and Mom's Kiss

  • Episode 852: Blood Oath - Playdough Cookie - Orphan Socks - Jacob & Esau FIXED NOW

    April 26th, 2022  |  1 hr 11 mins

    UPDATE: Will (an idiot) originally posted a busted version of this episode with the audio of the first segment out of sync, EVEN THOUGH he also did that with the early release, and you'd think he'd learn. Anyway: If the audio on Blood Oath sounds weird, delete and re-download the episode and you should be fine. -Will

    This week's entries: Blood Oath, Playdough Cookie, Orphan Socks, and Jacob & Esau

  • Episode 851: Dream Catcher - Paschal's Candle - Divine Intervention - Holy Crown

    April 19th, 2022  |  56 mins 21 secs

    This week's episodes: Dream Catcher, Paschal's Candle, Divine Intervention, and Holy Crown

  • Episode 850: Telescope Lens, Mom's Lock, Dice Bag, and Blood Puppy

    April 12th, 2022  |  53 mins 56 secs

    Programming note: Everything To Guppy is switching to a once-per-week release schedule; instead of four episodes throughout the week, you'll now be getting the show in hour-long blocks (that still contain four episodes). Feel free to consume in a single GLUT OF CONTENT, or employ the "Pausing" button on your audio device to recreate the bite-sized schedule of yesteryear. Your potential is infinite, listener! The power is yours!

  • Episode 849: Bethany

    April 10th, 2022  |  18 mins 26 secs

    The PA-mind piloting the drone's body reached forward and casually turned the sinister ball.

  • Episode 848: Flat File

    April 9th, 2022  |  13 mins 17 secs

    They reached, at last, a door that seemed on the surface to be like all the others, but which was drenched in such psychic horror that its very knob seemed to be a malevolent Sphere O' Evil.

  • Episode 847: Blue Key

    April 7th, 2022  |  17 mins 38 secs

    The light in the hallway began to dim, not because the bulbs were burning less power, but as though a terrible gravity was dragging the very luminescence deep into the abyss.

  • Episode 846: Panic Button

    April 5th, 2022  |  13 mins 28 secs

    They walked past what felt like dozens of doors, all as nondescript as the ones before.

  • Episode 845: Bar Of Soap

    April 3rd, 2022  |  17 mins 25 secs

    Instead, the man turned like a broken puppet and began sulkily leading the Rangers down the hallway.

  • Episode 844: Friendship Necklace

    April 2nd, 2022  |  12 mins 5 secs

    Cleary, the drone operator had been hoping to blast his atoms to atomreens.

  • Episode 843: Charged Penny

    March 31st, 2022  |  13 mins 52 secs

    The tinny voice emerging from the man's mouth sounded vaguely disappointed as it crackled a terse "Proceed."

  • Episode 842: Devil's Crown

    March 29th, 2022  |  16 mins 57 secs

    "08151984 That's Not Just My Birthday I Promise Omega," Friendship Ranger 3 replied.

  • Episode 841: The Shell

    March 27th, 2022  |  20 mins 38 secs

    "Authorization codex?" it intoned a new voice, thick with the hearty tang of bureaucratic menace.

  • Episode 840: Perfection

    March 26th, 2022  |  12 mins 58 secs

    His voice was suddenly replaced by the hiss and crack of the PA system embedded in his larynx.